SALT AND POLYMORPH OF PYRAZOLOPYRIMIDINONE COMPOUND AND DRUG COMPOSITION, PREPARATION METHOD AND USE THEREOF.

摘要

The present invention relates to salts and a pharmaceutically acceptable polymorph, solvate, hydrate, dehydrate, co-crystal, anhydride or amorphous form of a novel pyrazolopyrimidinone compound as shown in general formula (I), and to a pharmaceutical composition and a pharmaceutical unit dosage form comprising same, wherein X represents an organic or inorganic acid, preferably maleic acid, succinic acid, hydrochloric acid, methylsulfonic acid and the like. The present invention further relates to a co-crystal or a composite of the pyrazolopyrimidinone compound, and a pharmaceutical composition comprising same. The present invention also relates to a preparation method of the abovementioned substances, and the use thereof and pharmaceutical preparations comprising these salts and crystal forms.