发明名称 |
ASSAY AND METHOD FOR IDENTIFYING COMPOUNDS TO TREAT TAUOPATHIES |
摘要 |
The invention relates to methods and assays for identifying compounds as candidates in the development of a drug for the treatment of various diseases including those associated with pathological Tau. The invention also relates to methods and assays for identifying compounds for the treatment of various diseases including those associated with pathological Tau. The invention also relates to cell lines and constructs for use in an assay of the invention. The methods and assays identify a compound as useful in the treatment of a tauopathy if said compound modulates Sill expression or activity. |
申请公布号 |
WO2014134685(A1) |
申请公布日期 |
2014.09.12 |
申请号 |
WO2014AU00225 |
申请日期 |
2014.03.06 |
申请人 |
THE UNIVERSITY OF SYDNEY |
发明人 |
ITTNER, LARS MATTHIAS;VAN EERSEL, JANET |
分类号 |
G01N33/68;C12N15/09;C12Q1/68;C40B30/04 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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