GENE SIGNATURE TO PREDICT HOMOLOGOUS RECOMBINATION (HR) DEFICIENT CANCER
摘要
<p>Methods for identifying and treating cancers that are homologous recombination (HR)-repair defective. In some aspects, HR defective cancers are treated with a PARP inhibitor therapy. Methods for sensitizing cancers to a PARP inhibitor therapy are also provided.</p>
申请公布号
WO2014138101(A1)
申请公布日期
2014.09.12
申请号
WO2014US20376
申请日期
2014.03.04
申请人
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
发明人
LIN, CHUN-JEN;PENG, GUANG;LIN, SHIAW-YIH;MILLS, GORDON
