发明名称 |
METHODS OF TREATING ACUTE KIDNEY INJURY |
摘要 |
Methods are provided for treating acute kidney injury in a subject, particularly ischemia-induced kidney injury and/or hypoxia-induced kidney injury. The methods comprise administering to the subject an ETA receptor antagonist, such as atrasentan or a pharmaceutically acceptable salt thereof. Methods of diagnosing and treating such kidney injuries are also provided. Methods of reducing or preventing loss of kidney function and/or renal mass or volume, and methods of delaying progression to chronic kidney disease are also provided. |
申请公布号 |
WO2014138738(A1) |
申请公布日期 |
2014.09.12 |
申请号 |
WO2014US22688 |
申请日期 |
2014.03.10 |
申请人 |
ABBIVE INC.;FRED HUTCHINSON CANCER RESEARCH CENTER |
发明人 |
ZAGER, RICHARD A.;ANDRESS, DENNI |
分类号 |
C07K16/18;A61P13/12 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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