HYDROGEL AND METHOD FOR PRODUCING SAME

摘要

A hydrogel is provided which is obtained by reacting an azide group and a cyclooctyne group in the absence of a catalyst, especially in the absence of a copper catalyst. The hydrogel has: (a) a first polymer moiety composed of hyaluronic acid, carboxymethyl dextran or the like; (b) a second polymer moiety composed of hyaluronic acid, carboxymethyl dextran or the like, said second polymer moiety being of a kind that is same as or different from the kind of the moiety (a) and is composed of a molecule different from the moiety (a); and (c) a triazole ring group or a derivative group thereof.

主权项

1. A hydrogel comprising:
a) a first polymer section selected from the group consisting of hyaluronic acid, carboxymethyl dextran, cellulose derivatives, and chitosan; b) a second polymer section, selected from the group consisting of hyaluronic acid, carboxymethyl dextran, cellulose derivatives, and chitosan, that may be the same as or different from a), but comprising a different molecule; and c) a triazole ring group or derivative group thereof; the hydrogel having a structure such that the a) first polymer section and b) second polymer section are crosslinked via the mediation of the c) triazole ring group or derivative group thereof.