| 发明名称 |
SUBSTITUTED CARBAMOYLMETHYLAMINO ACETIC ACID DERIVATIVES AS NOVEL NEP INHIBITORS |
| 摘要 |
<p>PROBLEM TO BE SOLVED: To provide novel compounds which are useful as neutral endopeptidase inhibitors, e.g. as inhibitors of the ANF-degrading enzyme in mammals.SOLUTION: The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.</p> |
| 申请公布号 |
JP2014167015(A) |
申请公布日期 |
2014.09.11 |
| 申请号 |
JP20140096844 |
申请日期 |
2014.05.08 |
| 申请人 |
NOVARTIS AG |
发明人 |
IWAKI YUKI;KAWANAMI TOSHIO;KSANDER GARY MICHAEL;MOGI MUNEHITO |
| 分类号 |
C07D231/38;A61K31/41;A61K31/415;A61K31/421;A61P1/04;A61P1/14;A61P3/00;A61P3/04;A61P3/10;A61P3/14;A61P9/04;A61P9/10;A61P9/12;A61P11/00;A61P11/06;A61P13/12;A61P15/00;A61P15/10;A61P17/02;A61P25/04;A61P25/08;A61P25/18;A61P25/24;A61P25/28;A61P27/02;A61P27/06;A61P29/00;A61P31/04;A61P35/02;A61P43/00;C07D257/06;C07D261/14 |
主分类号 |
C07D231/38 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
