| 发明名称 |
PROCESS FOR THE PRODUCTION OF GAMMA-AMINOBUTYRIC ACID |
| 摘要 |
The present invention relates to a novel method for the fermentative production of gamma-aminobutyric acid (GABA) by cultivating a recombinant microorganism expressing an enzyme having a glutamate decarboxylase activity. The present invention also relates to corresponding recombinant hosts, recombinant vectors, expression cassettes and nucleic acids suitable for preparing such hosts as well as to a method for preparing polyamides making use of GABA as obtained fermentative production. |
| 申请公布号 |
US2014256005(A1) |
申请公布日期 |
2014.09.11 |
| 申请号 |
US201414289731 |
申请日期 |
2014.05.29 |
| 申请人 |
Zelder Oskar;Jeong Weol Kyu;Klopprogge Corinna;Herold Andrea;Schröder Hartwig |
发明人 |
Zelder Oskar;Jeong Weol Kyu;Klopprogge Corinna;Herold Andrea;Schröder Hartwig |
| 分类号 |
C12P13/00;C12P13/02;C12N9/88 |
主分类号 |
C12P13/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for the fermentative production of gamma-aminobutyric acid (GABA), comprising cultivating a recombinant microorganism derived from a parent microorganism having the ability to produce glutamate and additionally having the ability to express a heterologous glutamate decarboxylase (E.C. 4.1.1.15), wherein said microorganism is a Corynebacterium, so that glutamate is converted to GABA. |
| 地址 |
Speyer DE |
