发明名称 3,4-DI-SUBSTITUTED PYRIDINE COMPOUND, METHODS OF USING AND COMPOSITIONS COMPRISING THE SAME
摘要 2-((3-(4-cyanonaphthalen-1-yl)pyridin-4-yl)thio)-2-methylpropanoic acid is useful in the modulation of blood or serum uric acid levels. In some embodiments, 2-((3-(4-cyanonaphthalen-1-yl)pyridin-4-yl)thio)-2-methylpropanoic acid is used in the treatment or prevention of disorders related to aberrant levels of uric acid. In some embodiments, 2-((3-(4-cyanonaph-thalen-1-yl)pyridin-4-yl)thio)-2-methylpropanoic acid is used for reducing serum uric acid levels in a human. Also described herein are compositions comprising 2-((3-(4-cyanonaphthalen-1-yl)pyridin-4-yl)thio)-2-methylpropanoic acid, and their use in the modulation of blood or serum uric acid levels.
申请公布号 US2014256748(A1) 申请公布日期 2014.09.11
申请号 US201214355480 申请日期 2012.10.02
申请人 ARDEA BIOSCIENCES, INC. 发明人 Yeh Li-Tain;Quart Barry D.
分类号 C07D213/70;A61K45/06;A61K31/4418 主分类号 C07D213/70
代理机构 代理人
主权项 1. A compound for use in reducing serum uric acid levels in a human, wherein the compound is 2-((3-(4-cyanonaphthalen-1-yl)pyridin-4-yl)thio)-2-methylpropanoic acid, or a pharmaceutically acceptable salt thereof.
地址 San Diego CA US
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