发明名称 |
3,4-DI-SUBSTITUTED PYRIDINE COMPOUND, METHODS OF USING AND COMPOSITIONS COMPRISING THE SAME |
摘要 |
2-((3-(4-cyanonaphthalen-1-yl)pyridin-4-yl)thio)-2-methylpropanoic acid is useful in the modulation of blood or serum uric acid levels. In some embodiments, 2-((3-(4-cyanonaphthalen-1-yl)pyridin-4-yl)thio)-2-methylpropanoic acid is used in the treatment or prevention of disorders related to aberrant levels of uric acid. In some embodiments, 2-((3-(4-cyanonaph-thalen-1-yl)pyridin-4-yl)thio)-2-methylpropanoic acid is used for reducing serum uric acid levels in a human. Also described herein are compositions comprising 2-((3-(4-cyanonaphthalen-1-yl)pyridin-4-yl)thio)-2-methylpropanoic acid, and their use in the modulation of blood or serum uric acid levels. |
申请公布号 |
US2014256748(A1) |
申请公布日期 |
2014.09.11 |
申请号 |
US201214355480 |
申请日期 |
2012.10.02 |
申请人 |
ARDEA BIOSCIENCES, INC. |
发明人 |
Yeh Li-Tain;Quart Barry D. |
分类号 |
C07D213/70;A61K45/06;A61K31/4418 |
主分类号 |
C07D213/70 |
代理机构 |
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代理人 |
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主权项 |
1. A compound for use in reducing serum uric acid levels in a human, wherein the compound is 2-((3-(4-cyanonaphthalen-1-yl)pyridin-4-yl)thio)-2-methylpropanoic acid, or a pharmaceutically acceptable salt thereof. |
地址 |
San Diego CA US |