发明名称 COMPOUNDS ACTIVE AT NOVEL SITE ON RECEPTOR-OPERATED CALCIUM CHANNELS USEFUL FOR TREATMENT OF NEUROLOGICAL DISORDERS AND NEUROPATHY
摘要 <p>PROBLEM TO BE SOLVED: To provide compounds useful for curative treatment of neurodegenerative disease, or useful as a muscle relaxant, an analgesic, or an adjunct in general anesthesia.SOLUTION: The invention provides compounds represented by the specified structure or pharmaceutically acceptable salts thereof. [Each X is OH or OCH3; each R1 is independently C1-C5 lower alkyl; and each R2 is independently H or C1-C5 lower alkyl; where R1 and R2 on the nitrogen atom are identical.]</p>
申请公布号 JP2014166987(A) 申请公布日期 2014.09.11
申请号 JP20140005535 申请日期 2014.01.16
申请人 NPS PHARMACEUTICALS INC 发明人 MUELLER ALAN L;VAN WAGENEN BRADFORD C;DELMAR ERIC G;BALANDRIN MANUEL F;MOE SCOTT T;ARTMAN LINDA D;BARMORE ROBERT M
分类号 A61K31/405;C07C215/54;A61K31/135;A61K31/136;A61K31/137;A61K31/138;A61K31/14;A61K31/165;A61K31/17;A61K31/295;A61K31/381;A61K31/40;A61K31/403;A61K31/404;A61K31/4045;A61K31/4409;A61K31/4462;A61K31/4465;A61K45/00;A61P9/10;A61P9/12;A61P21/02;A61P23/00;A61P25/00;A61P25/04;A61P25/08;A61P25/14;A61P25/16;A61P25/22;A61P25/28;A61P43/00;C07C211/27;C07C211/29;C07C217/62;C07C233/22;C07C235/34;C07C237/22;C07C279/12;C07D209/18;G01N33/53;G01N33/566 主分类号 A61K31/405
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