发明名称 SYSTEM AND METHOD FOR PHARMACOVIGILANCE
摘要 A method, computer-readable storage medium, and system for analyzing a relationship between one or more agents and one or more clinical outcomes. The method includes: receiving a selection of one or more agents; receiving a selection of one or more clinical outcomes; for each of the one or more agents, analyzing clinical data stored in a database to determine a number of occurrences of each of the one or more clinical outcomes when the agent is administered; for each of the one or more agents, calculating a risk score for each clinical outcome corresponding to the number of occurrences of the clinical outcome; and outputting the risk scores to a graphical display.
申请公布号 US2014257844(A1) 申请公布日期 2014.09.11
申请号 US201414286102 申请日期 2014.05.23
申请人 Aetna, Inc. 发明人 MEHTA Rajesh Revachand;WEI Henry George;STEINBERG Gregory Brian
分类号 G06F19/00 主分类号 G06F19/00
代理机构 代理人
主权项 1. A method for analyzing a relationship between an agent and one or more clinical outcomes, the method comprising: receiving a selection of a first agent; receiving a selection of one or more clinical outcomes; analyzing, by a processor included in a computing device, clinical data stored in a database to determine a number of occurrences of each of the one or more clinical outcomes when the first agent is administered; calculating, by the processor, for the first agent, a first set of risk scores for each of the one or more clinical outcomes, wherein calculating the risk score for a clinical outcome includes measuring a statistical significance of a relationship between the first agent and the clinical outcome based on a total number of patients in an entire population, a number of patients to whom the first agent is administered, a number of occurrences of the clinical outcome when the first agent is administered, and a total number of patients in the entire population that experienced the clinical outcome; outputting the first set of risk scores to a graphical display device, wherein, for the first agent, a first risk score indicates that the first agent is not the cause of a first clinical outcome for a first sub-population that is a subset of the entire population; and generating a first hypothesis by the processor that is based on the first risk score that indicates that the first agent is not the cause of the first clinical outcome for the first sub-population.
地址 Hartford CT US