| 发明名称 |
COMPOSITIONS AND METHODS OF INHIBITING NEURONAL CELL DEATH |
| 摘要 |
A method of inhibiting β-amyloid (Aβ) induced neuronal cell death includes administering to a neuronal cell exposed to a neurotoxic amount of Aβ a therapeutically effective amount of cell penetrating peptide (CPP). The CPP has an amino acid sequence that has at least 80% sequence identity to about 5 to about 41 consecutive amino acids of SEQ ID NO: 1. |
| 申请公布号 |
US2014256039(A1) |
申请公布日期 |
2014.09.11 |
| 申请号 |
US201414279432 |
申请日期 |
2014.05.16 |
| 申请人 |
Case Western Reserve University |
发明人 |
Matsuyama Shigemi |
| 分类号 |
C12N5/0793 |
主分类号 |
C12N5/0793 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of inhibiting β-amyloid (Aβ) induced neuronal cell death, the method comprising:
administering to a neuronal cell exposed to a neurotoxic amount of Aβ a therapeutically effective amount of cell penetrating peptide (CPP), the CPP having an amino acid sequence that has at least 80% sequence identity to about 5 to about 41 consecutive amino acids of SEQ ID NO: 1. |
| 地址 |
Cleveland OH US |
