发明名称 Compositions and Methods for Inhibiting Viral Adhesion
摘要 The present invention provides compositions and methods for treating or preventing viral infections.
申请公布号 US2014256019(A1) 申请公布日期 2014.09.11
申请号 US201414196927 申请日期 2014.03.04
申请人 Recopharma AB 发明人 Holgersson Jan
分类号 C12N7/00 主分类号 C12N7/00
代理机构 代理人
主权项 1. A method of decreasing adhesion of a virus to a cell, comprising: contacting the virus with a fusion polypeptide, wherein the fusion polypeptide comprises a first polypeptide operably linked to a second polypeptide wherein the first polypeptide carries at least one glycan selected from the group consisting of: a) a Siaα3Galα4GlcNAcβ3 glycan, b) a Siaα3Galβ3GlcNAcβ3 glycan, c) a Siaα6Galβ4GlcNAcβ3 glycan, and d) a Siaα6Galβ3GlcNAcβ3 glycan, and the second polypeptide comprises at least a region of an immunoglobulin polypeptide.
地址 Goteborg SE
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