发明名称 |
PHARMACEUTICAL COMPOSITION AND ADMINISTRATIONS THEREOF |
摘要 |
The present invention relates to pharmaceutical compositions containing a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition. |
申请公布号 |
US2014255483(A1) |
申请公布日期 |
2014.09.11 |
申请号 |
US201414286856 |
申请日期 |
2014.05.23 |
申请人 |
Vertex Pharmaceuticals Incorporated |
发明人 |
Dokou Eleni;Jamzad Shahla;Caesar, JR. John P.;Fawaz Majed;Das Laura;Gu Chong-Hui;Hurter Patricia Nell;Israni Meghna Jai;Johnston Meghan M.;Knezic Dragutin;Kuzmission Andrew G.;Wang HongRen |
分类号 |
C07D215/56;A61K9/20;A61K9/16 |
主分类号 |
C07D215/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Boston MA US |