| 发明名称 |
ANTI-TNF-ANTI-IL-17 BISPECIFIC ANTIBODIES |
| 摘要 |
Bispecific antibodies are provided that specifically bind both Tumor Necrosis Factor alpha (TNFα) and Interleukin-17 (IL-17). The bispecific antibodies of the invention are useful for treating various autoimmune diseases, including Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA), and Ankylosing Spondylitis (AS). |
| 申请公布号 |
US2014255406(A1) |
申请公布日期 |
2014.09.11 |
| 申请号 |
US201414195885 |
申请日期 |
2014.03.04 |
| 申请人 |
Eli Lilly and Company |
发明人 |
Allan Barrett;Glasebrook Andrew Lawrence;Lu Jirong;Tang Ying;Witcher Derrick Ryan;Leung Donmienne Doen Mun;Yachi Pia Pauliina;Vendel Andrew Charles |
| 分类号 |
C07K16/24 |
主分类号 |
C07K16/24 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A bispecific antibody comprising a first polypeptide and a second polypeptide, wherein the first polypeptide has amino acid sequence of SEQ ID NO: 1, and the second polypeptide has an amino acid sequence of SEQ ID NO: 2. |
| 地址 |
Indianapolis IN US |
