发明名称 CRYSTALLINE FORM OF A QUINOLINONE-CARBOXAMIDE COMPOUND
摘要 The invention provides a crystalline hydrochloride salt of 1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid {(1S,3R,5R)-8-[(R)-2-hydroxy-3-(methanesulfonyl-methyl-amino)propyl]-8-azabicyclo[3.2.1]oct-3-yl}amide or a solvate thereof. The invention also provides pharmaceutical compositions comprising such crystalline salt forms, methods of using such crystalline salt forms to treat diseases associated with 5-HT4 receptor activity, and processes useful for preparing such crystalline salt forms.
申请公布号 US2014256769(A1) 申请公布日期 2014.09.11
申请号 US201414150059 申请日期 2014.01.08
申请人 Fatheree Paul R.;Turner S. Derek;Goldblum Adam A.;Chao Robert S.;Genov Daniel 发明人 Fatheree Paul R.;Turner S. Derek;Goldblum Adam A.;Chao Robert S.;Genov Daniel
分类号 C07D451/04 主分类号 C07D451/04
代理机构 代理人
主权项
地址 San Francisco CA US