| 发明名称 |
STENTS HAVING CONTROLLED ELUTION |
| 摘要 |
Provided herein is a device comprising a stent and a coating on the stent; wherein the coating comprises at least one polymer and at least one active agent; wherein at least part of the active agent is in crystalline form. |
| 申请公布号 |
US2014257465(A1) |
申请公布日期 |
2014.09.11 |
| 申请号 |
US201214238677 |
申请日期 |
2012.08.10 |
| 申请人 |
MICELL TECHNOLOGIES, INC. |
发明人 |
McClain James B.;Taylor Charles Douglas;Carlyle Wenda C. |
| 分类号 |
A61L31/16;A61L31/10;A61L31/02;A61L31/14 |
主分类号 |
A61L31/16 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A device comprising
a. a stent comprising a cobalt-chromium alloy; and b. a coating on the stent; wherein the coating comprises at least one polymer and at least one crystalline active agent; wherein the level of active agent degradation after two weeks incubation in a serum-supplemented cell culture medium at 37° C. is significantly reduced for the device as compared to a device comprising a metal cobalt-chromium stent and a coating comprising at least one polymer and at least one amorphous active agent. |
| 地址 |
Durham NC US |
