SYSTEM AND METHOD OF DETECTING AND PREDICTING SEIZURES

摘要

The present invention describes systems and methods for predicting and detecting a seizure in a subject. The methods of the invention comprise measuring interneuron synchrony in terms of the coherence between interneuron action potentials and local field potential oscillations. In one embodiment, the detection of specific patterns of coherence, correlation and firing rate of interneurons predicts an upcoming seizures.

主权项

1. A method of predicting a seizure in a subject, comprising:
recording single neuron activity for a plurality of interneurons; recording local field potential (LFP); and measuring interneuron synchrony; wherein detection of a specific pattern of interneuron activity and interneuron synchrony signifies an increased likelihood of a seizure.