| 发明名称 |
Multi-CBV Vaccine for Preventing or Treating Type I Diabetes |
| 摘要 |
The invention is directed to a vaccine comprising: i) coxsackie B virus CBV1 and CBV2, and ii) at least one coxsackie B virus selected from CBV3, CBV4, CBV5 and CBV6. The CBVs are present in the vaccine in inactivated form, in the form of a component of the virus or as an antibody against the virus. The vaccine is effective in preventing and treating type 1 diabetes. So is an anti-coxsackie B virus composition provided. |
| 申请公布号 |
US2014255425(A1) |
申请公布日期 |
2014.09.11 |
| 申请号 |
US201214352585 |
申请日期 |
2012.10.18 |
| 申请人 |
Vactech Oy |
发明人 |
Hyöty Heikki;Knip Mikael;Laitinen Olli;Tolonen Outi;Pulkki Minna;Oikarinen Sami;Honkanen Hanna-Riikka;Lecouturier Valérie;Almond Jeffrey;Flodström-Tullberg Malin |
| 分类号 |
A61K39/125;C07K16/10 |
主分类号 |
A61K39/125 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for preventing or treating type 1 diabetes in a subject in need thereof comprising administering to the subject a vaccine comprising:
i) coxsackie B virus CBV1 and CBV2 in inactivated form or in the form of a component of said virus, and
at least one coxsackie B virus selected from the group consisting of CBV3, CBV4, CBV5 and CBV6 in inactivated form or in the form of a component of said virus for use in preventing or treating type 1 diabetes. |
| 地址 |
Tampere FI |
