Bispecific Molecules That Are Immunoreactive with Immune Effector Cells of a Companion Animal That Express an Activating Receptor and Cells That Express B7-H3 and Uses Thereof

摘要

The present invention relates to bispecific molecules that are immunoreactive to an activating receptor of a companion animal immune effector cell and to B7-H3, and to the use of such bispecific molecules in the treatment of cancer in companion animals.

主权项

1. A bispecific molecule comprising:
(A) a first epitope-binding domain, said first epitope-binding domain being capable of binding to an epitope of a protein expressed on the surface of an immune effector cell of a companion animal, wherein said immune effector cell expresses an activating receptor; (B) a second epitope-binding domain, said second epitope-binding domain being capable of binding to an epitope of B7-H3 of the companion animal.