发明名称 PEGYLATED TYROSYL-TRNA SYNTHETASE POLYPEPTIDES
摘要 The present invention provides PEGylated tyrosyl-tRNA synthetase (YRS) polypeptides, compositions comprising the same, and methods of using such polypeptides and compositions for treating or diagnosing a variety of conditions. The PEGylated YRS polypeptides of the invention have improved controlled release properties, stability, half-life, and other pharmacokinetic properties compared to non-PEGylated YRS polypeptides.
申请公布号 US2014255378(A1) 申请公布日期 2014.09.11
申请号 US201214237544 申请日期 2012.08.08
申请人 Watkins Jeffrey D.;Buechler Ying Ji;Wu Chi-Fang;Do Minh-Ha;Vasserot Alain P.;Mendlein John D. 发明人 Watkins Jeffrey D.;Buechler Ying Ji;Wu Chi-Fang;Do Minh-Ha;Vasserot Alain P.;Mendlein John D.
分类号 C12N9/00 主分类号 C12N9/00
代理机构 代理人
主权项
地址 Encinitas CA US