发明名称 |
COMPOSITIONS COMPRISING NECROSIS INHIBITORS, SUCH AS NECROSTATINS, ALONE OR IN COMBINATION, FOR PROMOTING AXON REGENERATION AND NERVE FUNCTION, THEREBY TREATING CNS DISORDERS |
摘要 |
Provided are methods for promoting axon regeneration of a Central Nervous System (CNS) neuron and promoting nerve function following injury to a CNS neuron, for example, brain and/or spinal cord injury. Axon regeneration in a CNS neuron or nerve function following injury to a CNS neuron can be promoted by administering a necrosis inhibitor either alone or in combination with an apoptosis inhibitor to a subject suffering from a CNS disorder, wherein a symptom of the CNS disorder is axon degeneration. |
申请公布号 |
EP2773341(A2) |
申请公布日期 |
2014.09.10 |
申请号 |
EP20120780381 |
申请日期 |
2012.10.22 |
申请人 |
MASSACHUSETTS EYE & EAR INFIRMARY |
发明人 |
VAVVAS, DEMETRIOS |
分类号 |
A61K31/27;A61K31/4178;A61K45/06;A61P25/28 |
主分类号 |
A61K31/27 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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