发明名称 |
ATTENUATED PESTIVIRUS |
摘要 |
<p>The present invention relates to recombinant attenuated pestiviruses, in particular to recombinant attenuated CSFV, BVDV, or BDV, wherein said recombinant attenuated pestivirus does not produce a dimeric Erns glycoprotein. The present invention also relates to immunogenic compositions comprising such a pestivirus as well to a method of attenuating a pestivirus comprising the step of modifying the Erns glycoprotein by a deletion, insertion or substitution wherein such modification results in a non dimeric Erns glycoprotein.</p> |
申请公布号 |
EP2303320(B1) |
申请公布日期 |
2014.09.10 |
申请号 |
EP20090769297 |
申请日期 |
2009.06.24 |
申请人 |
BOEHRINGER INGELHEIM VETMEDICA GMBH |
发明人 |
MEYERS, GREGOR;TEWS, BIRKE ANDREA;SCHUERMANN, EVA-MARIA |
分类号 |
A61K39/12;C07K14/18;C12N7/04 |
主分类号 |
A61K39/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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