| 摘要 |
FIELD: medicine.SUBSTANCE: compounds are administered intraperitoneally, intravenously or orally in a dose of 0.5-90 mg/kg, particularly in a dose of 1-3 mg/kg 10-120 minutes before simulating a stress situation, particularly 30 minutes before simulating the stress situation that enables decreasing a damage area of the gastric mucosa by 1.5-5 times as compared to a reference group exposed to stress and taking no declared compounds. For the therapeutic purposes, these compounds are administered intraperitoneally, intravenously or orally in a dose of 0.5-90 mg/kg a day, particularly in a dose of 1 mg/kg a day for three days after the stress-induced damage of the gastric mucosa that enables decreasing the damage area of the gastric mucosa by 2.5-5 times as compared to the reference group exposed to stress and taking no declared compounds. The invention can be used for preventing and treating the stress-induced gastric ulcer.EFFECT: decreased area of the stress-induced ulceration.5 cl, 8 dwg, 11 ex |
