| 发明名称 |
PROCESS FOR PREPARING CHIRAL COMPOUNDS |
| 摘要 |
<p>The present invention is directed to the synthetic intermediate 2-[2-{4,6-dihydroxy-tetrahydropyran-2-yl]-isoindole-1,3-dione which can be prepared using a 2-deoxyribose-5-phosphate aldolase (DERA) chemoenzymatic process. The invention is also directed to the oxidation of 2-[2-{4,6-dihydroxy-tetrahydro-pyran-2-yl]-isoindole-1,3-dione to the corresponding lactone.</p> |
| 申请公布号 |
EP2185713(B1) |
申请公布日期 |
2014.09.10 |
| 申请号 |
EP20080788976 |
申请日期 |
2008.07.23 |
| 申请人 |
PFIZER PRODUCTS INC. |
发明人 |
BAUER, DAVID, WILLIAM;HU, SHANGHUI;O'NEILL, PADRAIG, MARY;WATSON, TIMOTHY, JAMES, NORMAN |
| 分类号 |
C12P17/10;C07D209/48;C07D319/08;C07D405/06;C12P7/62;C12P13/00 |
主分类号 |
C12P17/10 |
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