发明名称 |
METHODS FOR TREATING HYPERURICEMIA IN PATIENTS WITH GOUT USING HALOFENATE OR HALOFENIC ACID AND A SECOND URATE-LOWERING AGENT |
摘要 |
<p>Disclosed herein are pharmaceutical compositions, methods and kits for lowering the serum uric acid level of a subject and for the treatment of a condition associated with elevated serum uric acid levels comprising administering a composition comprising a first urate-lowering agent and a second urate-lowering agent. In some aspects the first urate-lowering agent is (-)- halofenate, (-)- halofenic acid, or a pharmaceutically acceptable salts thereof. In some aspects the second urate-lowering agent is an inhibitor of uric acid production, a uricosuric agent, a uricase, or a pharmaceutically acceptable salt thereof.</p> |
申请公布号 |
EP2773336(A1) |
申请公布日期 |
2014.09.10 |
申请号 |
EP20110875114 |
申请日期 |
2011.11.04 |
申请人 |
METABOLEX, INC. |
发明人 |
ROBERTS, BRIAN K.;SAHA, GOPAL CHANDRA;LAVAN, BRIAN EDWARD;MCWHERTER, CHARLES A. |
分类号 |
A61K31/19;A61K31/216;A61K31/426;A61K31/519;A61P19/06 |
主分类号 |
A61K31/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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