发明名称 |
TETRAHYDROTHIAZEPINE DERIVATIVE |
摘要 |
The present invention relates to a compound represented by the following general formula (I)
or a pharmacologically acceptable salt thereof having an excellent effect of inhibiting 11²-hydroxysteroid dehydrogenase type 1: General formula (I) wherein R 1 represents a phenyl group that may be substituted with 1 to 5 group(s) independently selected from substituent group A or a heterocyclic group that may be substituted with 1 to 4 group(s) independently selected from substituent group A; R 2 independently represents a halogen atom or a C 1 -C 6 alkyl group; n represents an integer of 0 to 2; and substituent group A represents the group consisting of halogen atoms, C 1 -C 6 alkyl groups, and so forth. |
申请公布号 |
EP2700643(A4) |
申请公布日期 |
2014.09.10 |
申请号 |
EP20120774851 |
申请日期 |
2012.04.17 |
申请人 |
DAIICHI SANKYO COMPANY, LIMITED |
发明人 |
MORI, MAKOTO;FUJII, KUNIHIKO;INUI, MASAHARU;BABA, TAKAYUKI;ONISHI, YUKARI;AOYAGI, ATSUSHI |
分类号 |
C07D513/04;A61K31/554;A61P1/16;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P5/46;A61P5/50;A61P9/10;A61P9/12;A61P19/10;A61P25/28;A61P27/06;A61P43/00;C07F7/18 |
主分类号 |
C07D513/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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