发明名称 |
Crystalline forms of the sodium salt of (4-{4-[5-(6-trifluoromethyl-pyridin-3-ylamino)-pyridin-2-yl]-phenyl}-cyclohexyl)-acetic acid |
摘要 |
The present invention relates to novel crystalline forms of (4-{4-[5-(6-Trifluoromethyl-pyridin-3-ylamino)-pyridin-2-yl]-phenyl}-cyclohexyl)-acetic acid, sodium and their use in the treatment or prevention of a condition or a disorder associated with DGAT1 activity in animals, particularly humans. It also relates to processes for making such novel crystalline forms. |
申请公布号 |
US8829194(B2) |
申请公布日期 |
2014.09.09 |
申请号 |
US201113876063 |
申请日期 |
2011.10.05 |
申请人 |
Novartis AG |
发明人 |
Sutton Paul Allen;Girgis Michael J.;Liang Jessica;Prashad Mahavir;Villhauer Edwin Bernard |
分类号 |
C07D213/04;A61K31/44;A61K31/444;C07D213/72;A61K45/06;C07D401/12 |
主分类号 |
C07D213/04 |
代理机构 |
|
代理人 |
Matovcik Lisa |
主权项 |
1. A crystalline form of the sodium salt of (4-{4-[5-(6-trifluoromethyl-pyridin-3-ylamino)-pyridin-2-yl]-phenyl}-cyclohexyl)-acetic acid of formula (II)in the form of Modification B, C, D, F, I, L, N, or O. |
地址 |
Basel CH |