发明名称 Crystalline forms of the sodium salt of (4-{4-[5-(6-trifluoromethyl-pyridin-3-ylamino)-pyridin-2-yl]-phenyl}-cyclohexyl)-acetic acid
摘要 The present invention relates to novel crystalline forms of (4-{4-[5-(6-Trifluoromethyl-pyridin-3-ylamino)-pyridin-2-yl]-phenyl}-cyclohexyl)-acetic acid, sodium and their use in the treatment or prevention of a condition or a disorder associated with DGAT1 activity in animals, particularly humans. It also relates to processes for making such novel crystalline forms.
申请公布号 US8829194(B2) 申请公布日期 2014.09.09
申请号 US201113876063 申请日期 2011.10.05
申请人 Novartis AG 发明人 Sutton Paul Allen;Girgis Michael J.;Liang Jessica;Prashad Mahavir;Villhauer Edwin Bernard
分类号 C07D213/04;A61K31/44;A61K31/444;C07D213/72;A61K45/06;C07D401/12 主分类号 C07D213/04
代理机构 代理人 Matovcik Lisa
主权项 1. A crystalline form of the sodium salt of (4-{4-[5-(6-trifluoromethyl-pyridin-3-ylamino)-pyridin-2-yl]-phenyl}-cyclohexyl)-acetic acid of formula (II)in the form of Modification B, C, D, F, I, L, N, or O.
地址 Basel CH