发明名称 |
Anticonvulsant combination therapy |
摘要 |
A method for alleviating and/or treating epileptic seizures comprising administering a pharmaceutical composition comprising (a) lacosamide and/or a pharmaceutically acceptable salt thereof; and (b) levetiracetam and/or a pharmaceutically acceptable salt thereof is described. |
申请公布号 |
US8828943(B2) |
申请公布日期 |
2014.09.09 |
申请号 |
US201213428419 |
申请日期 |
2012.03.23 |
申请人 |
UCB Pharma GmbH |
发明人 |
Stöhr Thomas |
分类号 |
A61K31/19;A61K31/195;A61K31/40;A61K31/4015;A61K31/53;A61K45/06 |
主分类号 |
A61K31/19 |
代理机构 |
Harness, Dickey & Pierce, P.L.C. |
代理人 |
Harness, Dickey & Pierce, P.L.C. |
主权项 |
1. A method for alleviating and/or treating epileptic seizures in a subject, the method comprising administering to the subject a pharmaceutical composition, wherein the pharmaceutical composition comprises (a) lacosamide and/or a pharmaceutically acceptable salt thereof; and (b) levetiracetam and/or a pharmaceutically acceptable salt thereof, optionally together with a pharmaceutically acceptable carrier, diluent and/or adjuvant, wherein (a) lacosamide and (b) levetiracetam are present in a fixed-dose ratio of about 3 parts lacosamide to at least about one part levetiracetam calculated on the ED50 values of the individual components (a) and (b), and wherein the pharmaceutical composition is in a single dosage form or the pharmaceutical composition is in separate dosage forms which are co-packaged. |
地址 |
Monheim DE |