发明名称 Anticonvulsant combination therapy
摘要 A method for alleviating and/or treating epileptic seizures comprising administering a pharmaceutical composition comprising (a) lacosamide and/or a pharmaceutically acceptable salt thereof; and (b) levetiracetam and/or a pharmaceutically acceptable salt thereof is described.
申请公布号 US8828943(B2) 申请公布日期 2014.09.09
申请号 US201213428419 申请日期 2012.03.23
申请人 UCB Pharma GmbH 发明人 Stöhr Thomas
分类号 A61K31/19;A61K31/195;A61K31/40;A61K31/4015;A61K31/53;A61K45/06 主分类号 A61K31/19
代理机构 Harness, Dickey & Pierce, P.L.C. 代理人 Harness, Dickey & Pierce, P.L.C.
主权项 1. A method for alleviating and/or treating epileptic seizures in a subject, the method comprising administering to the subject a pharmaceutical composition, wherein the pharmaceutical composition comprises (a) lacosamide and/or a pharmaceutically acceptable salt thereof; and (b) levetiracetam and/or a pharmaceutically acceptable salt thereof, optionally together with a pharmaceutically acceptable carrier, diluent and/or adjuvant, wherein (a) lacosamide and (b) levetiracetam are present in a fixed-dose ratio of about 3 parts lacosamide to at least about one part levetiracetam calculated on the ED50 values of the individual components (a) and (b), and wherein the pharmaceutical composition is in a single dosage form or the pharmaceutical composition is in separate dosage forms which are co-packaged.
地址 Monheim DE