| 发明名称 |
PIPERIDINYL-SUBSTITUTED ISOQUINOLONE DERIVATIVES AS RHO-KINASE INHIBITORS |
| 摘要 |
The invention relates to 6-piperidinyl-substituted isoquinolone derivatives of the formula (I) or isoquinoline derivatives of the formula (I~) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds. |
| 申请公布号 |
CA2615577(C) |
申请公布日期 |
2014.09.09 |
| 申请号 |
CA20062615577 |
申请日期 |
2006.07.20 |
| 申请人 |
SANOFI-AVENTIS |
发明人 |
PLETTENBURG, OLIVER;HOFMEISTER, ARMIN;KADEREIT, DIETER;BRENDEL, JOACHIM;LOEHN, MATTHIAS |
| 分类号 |
C07D401/12;A61K31/4725;A61P9/12 |
主分类号 |
C07D401/12 |
| 代理机构 |
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