| 发明名称 |
Process for resolving cyclopropyl diesters |
| 摘要 |
The present disclosure provides a method for the stereospecific hydrolysis of racemic 1,1-dialkyloxycarbonylcyclopropanes. |
| 申请公布号 |
US8828691(B2) |
申请公布日期 |
2014.09.09 |
| 申请号 |
US201313770219 |
申请日期 |
2013.02.19 |
| 申请人 |
Bristol-Myers Squibb Company |
发明人 |
Goswami Animesh;Guo Zhiwei;Qiu Yuping |
| 分类号 |
C12P7/62;C12P41/00 |
主分类号 |
C12P7/62 |
| 代理机构 |
|
代理人 |
Mingo Pamela A. |
| 主权项 |
1. A process for preparing a compound of formula (II) wherein
R1 is alkyl; andR2 is selected from alkenyl and alkyl; the process comprising: contacting a compound of formula (I) With Fusarium oxysporum Penicillin V Amidohydrolase. |
| 地址 |
Princeton NJ US |
