| 发明名称 | Protease inhibition | ||
| 摘要 | Proteins including engineered sequences which inhibit proteases are disclosed, including proteins having two or more engineered Kunitz domains, and uses of such proteins. | ||
| 申请公布号 | US8828703(B2) | 申请公布日期 | 2014.09.09 |
| 申请号 | US200611646148 | 申请日期 | 2006.12.27 |
| 申请人 | Dyax Corp. | 发明人 | Ladner Robert C. |
| 分类号 | C12N9/48;C12N15/00;C12P21/06;C12P21/04 | 主分类号 | C12N9/48 |
| 代理机构 | Wolf, Greenfield & Sacks, P.C. | 代理人 | Wolf, Greenfield & Sacks, P.C. |
| 主权项 | 1. An isolated protein comprising two to six engineered Kunitz domain sequences, wherein the protein comprises the amino acid sequence of SEQ ID NO:11, 54, 70, 71, 72, 73, 74, 102, 106, 107 or 127. | ||
| 地址 | Burlington MA US | ||