Nanopore device with graphene supported artificial lipid membrane

摘要

The invention features the use of graphene, a one atom thick planar sheet of bonded carbon atoms, in the formation of artificial lipid membranes. The invention also features the use of these membranes to detect the properties of polymers (e.g., the sequence of a nucleic acid) and identify transmembrane protein-interacting compounds.

主权项

1. A device comprising an artificial membrane on graphene with one or more apertures, wherein said artificial membrane comprises two lipid monolayers, each contacting one face of said graphene, and wherein the two lipid monolayers form a lipid bilayer within said one or more apertures in said graphene.