发明名称 Progesterone for the treatment or prevention of spontaneous preterm birth
摘要 A method for treating or preventing spontaneous preterm birth in pregnant women and improving neonatal morbidity and mortality. The method includes administering to a pregnant woman in need thereof an effective amount of progesterone sufficient to prolong gestation by minimizing the shortening or effacing of her cervix. Treatment and prophylaxis with progesterone in pregnant women having symptoms of short cervix has been clinically shown to increase neonatal health.
申请公布号 US8828981(B2) 申请公布日期 2014.09.09
申请号 US200812024756 申请日期 2008.02.01
申请人 发明人 Creasy George;O'Brien, Jr. John M.;DeFranco Emily A.;Muse Kenneth N.
分类号 A61K31/56;C07D215/04;A61M31/00;A61K31/57;A61K45/06 主分类号 A61K31/56
代理机构 Florek & Endres PLLC 代理人 Florek & Endres PLLC
主权项 1. A method for treating short cervix in a pregnant woman in order to treat the onset of preterm labor and subsequent preterm birth comprising: determining that a pregnant woman has a short cervix; and administering an effective amount of a formulation containing progesterone sufficient to prolong gestation by minimizing the shortening or effacing of the cervix.
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