Porous base matrix having formyl group, adsorbent using the porous base matrix, method for production of the porous base matrix, and method for production of the adsorbent

摘要

The present invention relates to a porous base matrix having formyl group, which base matrix has a structure represented by the formula (2) as a spacer, which structure is obtained by cleaving a group represented by the formula (1):;
wherein, R1 represents a group forming a five-membered ring or a six-membered ring with —CH(OH)—CH(OH)—; a method for producing the porous base matrix; and an adsorbent obtained by binding a ligand on the porous base matrix. By the present invention, a high-intensity base matrix for an adsorbent and an adsorbent are provided. The amount of a ligand leaked from the adsorbend is small.

主权项

1. A method for producing a porous base matrix having a formyl group, comprising steps of
allowing a halohydrin or a bis- or higher-functional epoxy compound to act on a raw material porous base matrix in order to introduce an epoxy group to the raw material porous base matrix, transforming the epoxy group into a glyceryl group, allowing a periodate salt to act on the glyceryl group in order to transform the glyceryl group into a monoformyl group, allowing a five-membered ring sugar containing at least an amino group or a six-membered ring sugar containing at least an amino group to react with the epoxy group and the monoformyl group in order to introduce a group represented by the general formula (1):wherein, R1 represents a group forming the sugar with —CH(OH)—CH(OH)—,
transforming the group (1) with a periodate salt into a group represented by the general formula (2):wherein, R1 is the same as the above.