发明名称 PROCESS FOR PRODUCTION OF PRASUGREL HYDROCHLORIDE HAVING HIGH PURITY
摘要 <p>An object of the present invention is to provide prasugrel hydrochloride with a reduced content of CATP, and the like. In the formulae, R represents a protecting group for a hydroxyl group. A method for producing prasugrel hydrochloride represented by the above formula is provided, characterized by comprising, in step (i), controlling, at low values, the temperature during the addition, optionally dropwise, of a chlorinating agent and the reaction temperature after the addition, optionally dropwise, of the chlorinating agent.</p>
申请公布号 PT2123656(E) 申请公布日期 2014.09.08
申请号 PT20080712139T 申请日期 2008.02.29
申请人 UBE INDUSTRIES LIMITED;DAIICHI SANKYO COMPANY, LIMITED 发明人 HIROYUKI MIYATA;YUKINORI WADA;NAOYUKI YOKOTA
分类号 C07D495/04;A61K31/4365;A61P7/02 主分类号 C07D495/04
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