TABLET CONTAINING 1-CYCLOPROPYL-8-(DIFLUOROMETHOXY)-7-[(1R)-1-METHYL-2, 3-DIHYDRO-1H-ISOINDOLE-5-YL]-4-OXO-1, 4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID METHANESULFONATE HYDRATE

摘要

(1) A tablet according to the present invention has a percentage content of 1-cyclopropyl-8-(difluoromethoxy)-7-[(1R)-1-methyl-2, 3-dihydro-1H-isoindole-5-yl]-4-oxo-1, 4-dihydroquinoline-3-carboxylic acid methanesulfonic acid hydrate of between 80 wt pcnt and 97.5 wt pcnt . (2) The tablet is smaller in size than 200mg of a commercially available Geninax tablet. (3) As a result, drug compliance is improved, (4) leachability is high, and (5) hardness and friability are high. (6) As a result, the present invention withstands film coating and transportation, and is useful as a tablet of methanesulfonic acid hydrate of chemical compound A.