发明名称 |
TRIFLUOROMETHYLATION AGENT POWDER, PRODUCTION METHOD THEREOF, AND PRODUCTION METHOD OF TRIFLUOROMETHYL GROUP-CONTAINING COMPOUND |
摘要 |
PROBLEM TO BE SOLVED: To provide a trifluoromethylation agent powder stable at room temperature and useful as a reaction reagent and a production method thereof, and a production method of trifluoromethyl group-containing compound.SOLUTION: A zinc powder is reacted with a trifluoromethyl iodide in a N,N-dimethylformamide solvent, and it is filtrated and concentrated to obtain a trifluoromethylation agent powder represented by general formula (1) that is (CF)ZnI (DMPU)(1), where DMPU represents N,N-dimethyl propylene urea and n represents an integer of 1 to 4, then it is reacted with substituted aromatic iodide in a presence of copper (I) catalyst to obtain a trifluoromethyl group-containing compound. |
申请公布号 |
JP2014162732(A) |
申请公布日期 |
2014.09.08 |
申请号 |
JP20130032699 |
申请日期 |
2013.02.22 |
申请人 |
TOKYO INSTITUTE OF TECHNOLOGY;TOSOH F-TECH INC |
发明人 |
MIKAMI KOICHI;NAKAMURA YUZO;NEGISHI KAZUYUKI;AIKAWA KOSUKE |
分类号 |
C07F3/06;C07B61/00;C07C67/307;C07C69/76;C07D213/61 |
主分类号 |
C07F3/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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