| 发明名称 |
Androgenreceptor modulerende forbindelser. |
| 摘要 |
<p>Compounds of formula (I) wherein R 1 to R 16 , A. B and E are as defined in the claims and pharmaceutically acceptable salts and esters thereof, are disclosed. The compounds of formula (I) possess utility as tissue-selective androgen receptor modulators (SARM) and are particularly useful as medicaments in the treatment of prostate cancer and other AR dependent conditions and diseases where AR antagonism is desired.</p> |
| 申请公布号 |
DK2493858(T3) |
申请公布日期 |
2014.09.08 |
| 申请号 |
DK20100781918T |
申请日期 |
2010.10.27 |
| 申请人 |
ORION CORPORATION |
发明人 |
HÖGLUND, IISA;KARJALAINEN, ARJA;HOLM, PATRIK;RASKU, SIRPA;WOHLFAHRT, GERD;TÖRMÄKANGAS, OLLI;SALO, HARRI;KNUUTTILA, PIA;VESALAINEN, ANNIINA |
| 分类号 |
C07D231/14;A61K31/416;A61K31/42;A61K31/438;A61K31/44;A61K31/4523;A61K31/497;A61K31/5377;A61P35/00;C07D401/12;C07D403/12;C07D405/12;C07D413/12;C07D417/12 |
主分类号 |
C07D231/14 |
| 代理机构 |
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