| 发明名称 |
N-TERMINAL DELETED GP120 IMMUNOGENS |
| 摘要 |
The present invention relates, in general, to human immunodeficiency virus (HIV), and in particular to a vaccine for HIV-1 and to methods of making and using same. |
| 申请公布号 |
US2014248311(A1) |
申请公布日期 |
2014.09.04 |
| 申请号 |
US201214130338 |
申请日期 |
2012.07.05 |
| 申请人 |
Kim Jerome;Harrison Stephen;Haynes Barton F.;Tomaras Georgia D.;Michael Nelson |
发明人 |
Kim Jerome;Harrison Stephen;Haynes Barton F.;Tomaras Georgia D.;Michael Nelson |
| 分类号 |
C07K14/005 |
主分类号 |
C07K14/005 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An immunogen comprising an HIV-1 Env gp120 or gp140, wherein the original about 4 to about 25 amino acids of the N-terminus of gp120 are deleted and wherein an N-terminal Herpes Simplex gD tag is not substituted for amino acids of the N-terminus of gp120. |
| 地址 |
Fort Detrick MD US |
