| 发明名称 |
USES AND COMPOSITIONS FOR TREATMENT OF PSORIATIC ARTHRITIS |
| 摘要 |
The invention provides methods, uses and compositions for the treatment of psoriatic arthritis. The invention describes methods and uses for treating psoriatic arthritis, wherein a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof, is used to psoriatic arthritis in a subject. Also described are methods for determining the efficacy of a TNFα inhibitor for treatment of psoriatic arthritis in a subject. |
| 申请公布号 |
US2014248215(A1) |
申请公布日期 |
2014.09.04 |
| 申请号 |
US201314010172 |
申请日期 |
2013.08.26 |
| 申请人 |
Hoffman Rebecca S.;Sasso Eric H.;Perdok Renee J.;Yan Philip;Weinberg Mark;Mease Phillip;Ritchlin Christopher T.;Gladman Dafna D. |
发明人 |
Hoffman Rebecca S.;Sasso Eric H.;Perdok Renee J.;Yan Philip;Weinberg Mark;Mease Phillip;Ritchlin Christopher T.;Gladman Dafna D. |
| 分类号 |
C07K16/24;A61K49/00 |
主分类号 |
C07K16/24 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of determining the efficacy of a TNFα inhibitor for treating psoriatic arthritis in a subject comprising:
determining an ACR20 response of a patient population having psoriatic arthritis who was administered the TNFα inhibitor, wherein an ACR20 response in at least about 39% of the patient population indicates that the TNFα inhibitor is an effective TNFα inhibitor for the treatment of psoriatic arthritis. |
| 地址 |
Wilmette IL US |
