| 发明名称 |
PHARMACEUTICAL COMPOSITIONS OF COMBINATIONS OF DIPEPTIDYL PEPTIDASE-4 INHIBITORS WITH ATORVASTATIN |
| 摘要 |
This invention relates to a bilayer pharmaceutical compositions comprising fixed-dose combinations of a dipeptidyl peptidase-4 inhibitor and atorvastatin, or a pharmaceutically acceptable salt thereof, methods of preparing such pharmaceutical compositions, and methods of treating Type 2 diabetes with such pharmaceutical compositions. |
| 申请公布号 |
US2014248345(A1) |
申请公布日期 |
2014.09.04 |
| 申请号 |
US201214350499 |
申请日期 |
2012.10.20 |
| 申请人 |
Merck Sharp & Dohme Corp. |
发明人 |
Sotthivirat Sutthilug;Fagan Edward J.;Chin Katherine H.;Woldu Abraham B.;DeLuca Charles;Ma Decheng;Wasylaschuk Walter R.;Rege Bhagwant |
| 分类号 |
A61K31/4985;A61K9/24;A61K31/40 |
主分类号 |
A61K31/4985 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pharmaceutical composition in the form of a bilayer tablet comprising:
(a) a first layer comprising about 20 to 45% by weight of a dipeptidyl peptidase-4 inhibitor, or a pharmaceutically acceptable salt thereof; and (b) a second layer comprising about 5 to 15% by weight of atorvastatin, or a pharmaceutically acceptable salt thereof. |
| 地址 |
Rahway NJ US |
