NOVEL INTRON SEQUENCES

摘要

The invention concerns the field of recombinant gene engineering. It concerns novel introns and compositions comprising such introns as well as a method to improve expression of polypeptides from nucleic acids such as cloned genes with heterologous introns, especially genes encoding antibodies and antibody derived fragments, and the production of various polypeptides in eukaryotic host cells using said novel intron sequences as heterologous introns.

主权项

1. An intron comprising a sequence at least 70%, 75%, 80%, 85%, 90%, 95%, 99%, 100% identical to SEQ ID NO:1 or SEQ ID NO:3.