| 发明名称 |
MULTISPECIFIC MUTATED ANTIBODY FAB FRAGMENTS. |
| 摘要 |
The invention relates to multispecific antibody constructs comprising Fab fragments having mutations at the interface of the CHI and CL domains, said mutations preventing heavy chain/light chain mispairing. |
| 申请公布号 |
MX2014000234(A) |
申请公布日期 |
2014.09.04 |
| 申请号 |
MX20140000234 |
申请日期 |
2012.07.06 |
| 申请人 |
UNIVERSITE DE LAUSANNE |
发明人 |
JEAN KADOUCHE;JEAN-PIERRE MACH;OLIVIER MICHIELIN;VINCENT ZOETE;JUSTYNA IWASZKIEWICZ;MARTINE CERUTTI;SYLVIE CHOBLET;JOSÉE GOLAY |
| 分类号 |
C07K16/46;A61K39/395 |
主分类号 |
C07K16/46 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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