发明名称 |
T CELL BALANCE GENE EXPRESSION, COMPOSITIONS OF MATTERS AND METHODS OF USE THEREOF |
摘要 |
<p>This invention relates generally to compositions and methods for identifying the regulatory network that modulates, controls or otherwise influences T cell balance, for example, Thl7 cell differentiation, maintenance and/or function, as well compositions and methods for exploiting the regulatory network that modulates, controls or otherwise influences T cell balance in a variety of therapeutic and/or diagnostic indications. This invention also relates generally to identifying and exploiting target genes and/or target gene products that modulate, control or otherwise influence T cell balance in a variety of therapeutic and/or diagnostic indications.</p> |
申请公布号 |
CA2902940(A1) |
申请公布日期 |
2014.09.04 |
申请号 |
CA20142902940 |
申请日期 |
2014.02.27 |
申请人 |
THE BROAD INSTITUTE, INC.;PRESIDENT AND FELLOWS OF HARVARD COLLEGE;THE BRIGHAM AND WOMEN'S HOSPITAL, INC.;MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
REGEV, AVIV;KUCHROO, VIJAY;PARK, HONGKUN;YOSEF, NIR;SHALEK, ALEXANDER K.;GAUBLOMME, JELLERT;JOLLER, NICOLE C.;WU, CHUAN;ANDERSON, ANA CARRIZOSA |
分类号 |
C12Q1/68;A61K39/39;C12N5/0783 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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