SELECTION OF PREFERRED SAMPLE HANDLING AND PROCESSING PROTOCOL FOR IDENTIFICATION OF DISEASE BIOMARKERS AND SAMPLE QUALITY ASSESSMENT

摘要

The subject invention relates to methods for obtaining biological samples of improved quality. It encompasses the identification of markers or proteins in biological samples that are altered due to variations in sample collection, handling and processing. They are also useful for correcting variations in measured results for disease biomarkers. Further, they can permit the rejection of samples or groups of samples as necessary if it is determined that their collection method was not in accordance with the predetermined protocol. Other advantages useful to the skilled artisan are described herein.