发明名称 |
High penetration prodrug compositions of peptides and peptide-related compounds |
摘要 |
Provided is a high penetration composition or high penetration prodrugs of peptide or peptide-related compound comprising functional unit, linker, and transportational unit. The functional unit is covalently linked to the transportational unit via the linker, and comprises a moiety of the peptide or the peptide-related compound. The transportational unit comprises protonatable amine group. The linker comprises chemical bond that is capable of being cleaved after the composition penetrates across a biological barrier. |
申请公布号 |
EP2660247(A3) |
申请公布日期 |
2014.09.03 |
申请号 |
EP20130170316 |
申请日期 |
2010.05.10 |
申请人 |
YU, CHONGXI;TECHFIELDS BIOCHEM CO. LTD |
发明人 |
YU, CHONGXI;XU, LINA;CHEN, YUHUA;YAN, BINBING;TU, SHIQIAN |
分类号 |
C07K7/06;A61K38/08;A61K38/10;A61K38/16;A61K47/48;A61P17/00;A61P25/00;C07K1/04;C07K7/08;C07K14/00 |
主分类号 |
C07K7/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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