发明名称 |
USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) |
摘要 |
<p>Methods are provided for treating a hematologic cancer comprising administering an anticancer agent to a subject identified as having an increased mobilization of a subpopulation of lymphocytes from a malignancy following administration of an irreversible Btk inhibitor. Methods also are provided for identification of subjects for treatment and the analysis of cells mobilized from a hematologic malignancy following administration of an irreversible Btk inhibitor.</p> |
申请公布号 |
EP2771010(A2) |
申请公布日期 |
2014.09.03 |
申请号 |
EP20120841068 |
申请日期 |
2012.10.19 |
申请人 |
PHARMACYCLICS, INC. |
发明人 |
BUGGY, JOSEPH J.;ELIAS, LAURENCE;FYFE, GWEN;HEDRICK, ERIC;LOURY, DAVID J.;MODY, TARAK D. |
分类号 |
A61K31/52;A61K31/337;A61K31/4184;A61K31/454;A61K31/475;A61K31/4965;A61K31/519;A61K31/5383;A61K31/704;A61K31/7076;A61P35/00 |
主分类号 |
A61K31/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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