发明名称 |
POLYPEPTIDES WITH ENHANCED ANTI-INFLAMMATORY AND DECREASED CYTOTOXIC PROPERTIES AND RELATING METHODS |
摘要 |
The invention provides a polypeptide containing at least one IgG Fc region, said polypeptide having a higher anti-inflammatory activity and a lower cytotoxic activity as compared to an unpurified antibody and methods of production of such polypeptide. |
申请公布号 |
EP2010566(B1) |
申请公布日期 |
2014.09.03 |
申请号 |
EP20070754846 |
申请日期 |
2007.04.03 |
申请人 |
THE ROCKEFELLER UNIVERSITY |
发明人 |
RAVETCH, JEFFREY, V.;YOSHIKATUS, KANEKO;NIMMERJAHN, FALK |
分类号 |
C07K16/00;A61K39/395;C07K16/06;C07K16/18 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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