发明名称 |
COMPOSITIONS AND METHODS FOR CARDIOVASCULAR DISEASE |
摘要 |
The present invention provides small molecule inhibitors of BMP signaling. These compounds may be used to reduce circulating levels of ApoB-100 or LDL. These compounds may also be used to treat or prevent acquired or congenital hypercholesterolemia or hyperlipoproteinemia; diseases, disorders, or syndromes associated with defects in lipid absorption or metabolism; or diseases, disorders, or syndromes caused by hyperlipidemia. |
申请公布号 |
EP2665726(A4) |
申请公布日期 |
2014.09.03 |
申请号 |
EP20120736510 |
申请日期 |
2012.01.20 |
申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
YU, PAUL, B.;DERWALL, MATHIAS;BLOCH, KENNETH, D.;MALHOTRA, RAJEEV |
分类号 |
C07D487/04;A61K31/519;A61P9/00;C07D401/04;C07D413/14 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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