发明名称 |
CHRYSOPHAENTIN ANTIMICROBIAL COMPOUNDS THAT INHIBIT FTSZ PROTEIN |
摘要 |
Embodiments of antimicrobial chrysophaentin compounds, pharmaceutical compositions including the chrysophaentin compounds, and methods for using the chrysophaentin compounds are disclosed. Some embodiments of the disclosed compounds are isolated from Chrysophaeum taylori. Certain embodiments of the chrysophaentin compounds inhibit FtsZ protein, thereby inhibiting the growth of clinically relevant bacteria, including drug-resistant strains. |
申请公布号 |
EP2539305(A4) |
申请公布日期 |
2014.09.03 |
申请号 |
EP20110748136 |
申请日期 |
2011.02.25 |
申请人 |
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
BEWLEY, CAROLE, A.;PLAZA, ALBERTO;KEFFER, JESSICA |
分类号 |
C07C43/295;C07D321/00 |
主分类号 |
C07C43/295 |
代理机构 |
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代理人 |
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地址 |
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